Does Progesterone Cause Cancer?
Many, including state authorities, make the mistake in thinking that progesterone and the synthetic progestins are one and the same, they are not. Therein lies the root of the misinformation that natural progesterone poses a cancer threat.
Emory University has been studying progesterone for 20 years now and have only found benefits. In fact, a study they completed last year on brain trauma victims, found it reversed the oedema that formed after the injury, with no adverse side affects. Interestingly 71% of the victims were men.
I do understand your concern, so below you will find links to several research papers on various cancers. Several of these studies show how progesterone actually protects against cancer by activating the gene p53, which is the gene involved in apoptosis. If this gene is inactive cells keep growing.
The hormone estrogen is a known initiator of heart disease and cancer, progesterone inhibits the production of estrogen.
There are many, many research papers showing the protective role progesterone plays in the body. It protects against hypertension, lowers blood fats, it prevents coronary hyperactivity, a sign of coronary artery disease, it does not increase breast, endometrial and ovarian cancer risk and can be protective against it, can prevent epilepsy, it improves vasomotor symptoms, it prevents miscarriages and much more.
Here is some information that will help you get a better understanding on the role of progesterone relative to cancer.
Cancer of hormonally sensitive tissue
There is increasing evidence that 95% of cancers are caused by environmental factors such as pollutants from agriculture and industry, processed food and the misuse of prescription drugs such as estrogen, whereas only 5% are related to our genes.
Various studies show we can alter the way our genes are expressed by changing the factors that influence them, such as those stated above. Continuing research, first started during the 90's, has identified a few genes that help control cell growth by producing substances that regulate cell division. If these genes are damaged by pollutants, by oxidation or by a lack of certain nutrients, the cells multiply rapidly and cancer can be the result.
Homocysteine (H) has been identified as a reliable marker for low levels of certain B vitamins and is indicative of a possible risk for getting over 50 common diseases, amongst them being cancer. There is now evidence that having a high H score adversely affects the rate of tumour growth.
A study reported on cancer in 2002 found an increase in cancers due to a lack of UV-B and vitamin D3. The researchers believe that mortality rates could be reduced by careful exposure to sunlight and taking vitamin D3 supplements.
It has now been recognised that if a mother has been exposed to high levels of natural or xeno-estrogens whilst pregnant, the foetus could be affected, leading to breast, ovarian and endometrial cancer in women and testicular, prostate and increasingly breast cancer in men.
Research has shown that the longer a women is exposed to her own natural estrogen, i.e. a long reproductive lifetime, the greater the chances of her getting cancer. Women with low levels of progesterone have a 5.4 greater chance of getting breast cancer with 10 times a greater chance of dying from all cancers. Breast cancer recurrence after a mastectomy is more likely if the surgery is performed in the first half of the cycle when estrogen is dominant than in the second half.
The contraceptive pill increases the risk of getting cervical cancer, the longer the duration of taking it, the greater the risk.
HRT (hormone replacement therapy), unopposed by progesterone, causes endometrial cancer. Studies published in 1995 found that women who had been exposed to HRT for longer than 5 years had a 32% increased risk of getting breast cancer, if combined with a progestin it went up to 41% and for those women who were post menopausal the risk went up to 71%, while the risk of getting ovarian cancer went up by 72%.
The latest evidence of estrogen and progestin causing problems in women comes from the Women's Health Initiative, which ended in 2003, 3 years early due to an increase in breast cancer, heart disease and strokes. The FDA has now ordered pharmaceutical firms to include a warning label on HRT boxes stating the increase. By 2004 the latest estrogen only arm of the WHI was halted due to an increase in the incidents of strokes.
Tamoxifen, a weak estrogenic drug used in the treatment of breast cancer, is classified as a carcinogen. It causes an increase in both endometrial and liver cancer.
Essential video viewing for any man over 40!
As water is now contaminated with estrogen from HRT and the contraceptive pill, plus those generated by industry, men are increasingly subjected to an excess, and with this comes an increase in the estrogen related cancers, prostate and testicular. If treated with estrogen for prostate cancer or after transsexual surgery there is an increased risk of men getting breast cancer. The older a man gets the more likely he is to suffer from estrogen dominance, which causes a decrease in his testosterone levels and an increase in di-hydrotestosterone, this in turn leads to a drop in libido and an increased likelihood of getting prostate hyperplasia or cancer.
There are at least 40, if not more, carcinogens to which we are exposed on a daily basis. Main concerns are:
- bleaches used for whitening flour etc
- charred food e.g. toast and browned meat
- chlorine in drinking water
- food preservatives
- all mineral oil, including liquid paraffin
- estrogen and xeno-estrogens
- industrial chemicals such as dioxin, PCB's and phthalates
- radiation from the sun
- nuclear power stations
- TV sets, computers and cell phones
- refined cooking oil and margarine
- tobacco smoke
- vehicle exhaust fumes
Use between 100/3ml-200/6ml mg of progesterone daily. More maybe needed, vary the amount used following symptoms as a guide. If radiation therapy is called for put the cream directly on the burn, as it has soothing, pain reducing and regenerative properties. Progesterone is neuroprotective, it prevents lipid peroxidation and confers vascular protection. As an anti-inflammatory agent, progesterone has been shown to reduce the response of natural killer cells as well as other known initiators of inflammation.
There is mounting evidence that many, 78 at the last count, if not all our modern diseases, syndromes and symptoms are possibly linked to a vitamin D deficiency, CANCER is one of them. It is extremely important that you have your vitamin D level tested. Please visit Benefits of Vitamin D and Vitamin D Council websites and take the time to view this video on cancer.
Another excellent video to watch is that of Dr Bruce Lipton who is one of the discoverers of epigenetics. He explains that it is possible to change the way a gene expresses itself via nutrition and our minds. Vitamin D being of extreme importance. The video is long but well worth the view. See here.
The Ketogenic Diet has produced some amazing results. Please read Dr Mercola's page on the diet under References.
Please Note: Cancer feeds off sugar - cut back or cut out!