NATPRO PROGESTERONE CREAM

What do I get when I order Natpro Progesterone Cream?

Tube - available in South Africa only

  • Each tube contains 60 grams (2 oz) of cream and 2000mg of progesterone
  • A tube, at the minimum dose of 100mg/3ml is sufficient for 20 days - see here
  • Natpro cream has a concentration of 3.33% progesterone or 33.33 milligrams per gram
  • Each tube comes with instructions 
  • Each tube contains: 
  • de-ionised water
  • caprylic/capric triglyceride (MCT Oil)
  • cetearyl olivate/sorbitan olivate
  • natural progesterone 2000mg Ph. Eur. USP JP
  • Populus Tremuloides (Aspen Bark)
  • vitamin E
  • dehydroxanthan gum

Dispenser - not available in South Africa

  • Each dispenser contains 100 grams (3.5 oz) of cream and 3,333mg progesterone - See here for recommended usage levels
  • Natpro cream has a concentration of 3.33% progesterone or 33.33 milligrams per gram
  • Each dispenser comes with an instructional pamphlet
  • Each dispenser contains:
  • de-ionised water
  • caprylic/capric triglyceride
  • cetearyl olivate/sorbitan olivate
  • natural progesterone Ph.Eur. USP. JP.
  • Populus tremuloides (Aspen Bark)
  • vitamin E
  • dehydroxanthan gum
  • Please note:  Natpro has an unopened shelf life of 18 months and is still valid for 6 months after the expiry date.


  • De-ionized water - this is an industry standard for water purification.
  • Caprylic/capric triglycerides - is a medium chain triglyceride of fractionated vegetable fatty acids extracted from coconuts. It is colourless, neutral in odour and taste, and has a very low viscosity. It has very good resistance to oxidation. It serves as a carrier and transport vehicle for active ingredients, as it penetrates the skin readily, being easily absorbed. It does not leave a greasy film and helps to retain moisture.
  • Progesterone Ph. Eur. USP JP - Is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals.  Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soy bean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone, they are used as starting points for the synthesis of progesterone. The progesterone used in Natpro is synthesised from the yam.
  • Cetearyl olivate / sorbitan olivate - a unique natural PEG-free organic emulsifier from olive oil. It reduces skin water loss, has a high moisturizing effect, is hypoallergenic and bio mimics the skin.
  • Populus Tremuloides (Aspen Bark) - a natural preservative made from non GM aspen trees. ‘Aspen bark extract’ as such is a unique discovery, as it is an effective natural replacement for commonly used harmful chemical preservatives. It also improves the emollience (the 'feel good' factor) of the cream.
  • dl-alpha tocopherol  Vitamin E - all emulsions made with vegetable oils have the potential to go rancid. For this reason dl-alpha tocopherol is used as it’s an in vitro antioxidant.
  • dehydroxanthan gum - is an Eco Certified, non GMO film former, fixative and emulsion stabilizer. It provides unprecedented hold under highly humid conditions without being tacky or flaking.


Natpro contains only vegetable substances. No animal has suffered or will ever suffer because of its production or use.

If you have any questions about Natpro Progesterone Cream

Contact Us

Natpro progesterone cream does not contain any toxic substances - such as growth hormones which are found in today's animal products. It contains no parabens either i.e. grapefruit seed extract. You are protected.

  • the progesterone in Natpro is identical to the progesterone your body makes. 'Progesterone Ph. Eur. USP JP' is derived principally from stigmasterol, a steroidal sapogenin. Phytosterols are chemically similar to cholesterol which is found in animals. Cholesterol is the starting point for the hormones made naturally in animals, including humans. Plants such as the soybean, Dioscorea species of yams, fenugreek, sisal, calabar bean, some lilies, yucca, some solanum species, maize and many more contain phytosterols, some of which are stigmasterol, diosgenin, sitosterol, campesterol, hecogenin, smilagenin, sarsasapogenin, solasodine. As these sterols have a similar molecular structure to progesterone, they are used as starting points for the synthesis of progesterone. In the southern United States the sweet potato (Ipomoea batatas) is called a yam, as are some edible members of the aroids. These plants do not contain any sapogenins. Don't confuse Natpro progesterone cream with a bean or yam "extract". Such extracts do not contain progesterone.
  • caprylic/capric triglyceride - is a 'medium chain' triglyceride of fractionated vegetable fatty acids extracted from coconut oil. It is colourless, neutral in odour and taste and has a very low viscosity. It has very good resistance to oxidation. It is an ideal 'carrier' for progesterone, as it penetrates the skin readily and is easily absorbed. It does not leave a greasy film and helps to retain moisture. Very importantly... it is not a mineral oil and is unrefined.

A closer look:

  1. Mineral oils, being petro-chemicals, are potentially harmful because they are "endochrine disruptors". They rob your body of the oil soluble vitamins A, D, E & K, and so deprive you of vital nutrients. Never use any product on your skin that contains mineral oils.
  2. Heating or refining any vegetable oil causes damage. The good "cis" fatty acids that are found in vegetable oils are turned into bad "trans" fatty acids and the result is highly carcinogenic. DO NOT use refined oils.
  • Vitamin E (dl-alpha tocopherol) - All emulsions made with vegetable oils have the potential to go rancid. For this reason dl-alpha tocopherol is used as it is an 'in vitro' antioxidant. Standard preparations contain only 0.1%, however, Natpro progesterone cream contains a further 0.2%.
  • The new two part emulsifier system, cetearyl olivate/sorbitan olivate - a unique natural PEG-free organic emulsifier from olive oil. It reduces skin water loss, has a high moisturizing effect, is hypoallergenic and biomimics the skin.
  • Aspen bark extract, a new natural organic preservative system is a natural organic preservative is a unique discovery as it is an effective natural replacement for commonly used harmful chemical preservatives such as the 'parabens'. It also improves the emollience (the 'feel good' factor) of the cream.
  • de-ionized water - this is a pure pharmaceutical grade standard

The correct Progesterone Concentration


When choosing a progesterone cream it is vital that it has the correct progesterone concentration.

The strength/concentration of many progesterone creams vary from 1.5% to 10%. This means a 1.5% cream contains 15mg progesterone per gram (g) or millilitre (ml). A 10% cream contains 100mg per gram (g) or millilitre (ml). So depending on the amount of progesterone needed for symptoms, the amount of cream must be taken into account. Natpro is a 3.3% cream, or contains 33.3mg per gram or ml.

It is also extremely important that you look at the ingredients in the cream, many contain estrogenic properties i.e. grapefruit seed extract etc, and many although it states that the cream is natural, contains chemical preservatives.

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